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Specific subtypes assessed included Alzheimers disease, vascular dementia, frontotemporal dementia, Parkinsons disease, extrapyramidal and movement disorders, and dementia with Lewy bodies

Farxiga FDA Approvals : Type 2 diabetes (adults): Approved 2014 Heart failure with reduced ejection fraction (HFrEF, adults): Approved 2020 Chronic kidney disease (adults): Approved 2021 Heart failure with preserved ejection fraction (HFpEF, adults): Approved 2022 Type 1 diabetes: Previously approved but withdrawn due to DKA risk Jardiance FDA Approvals : Type 2 diabetes (adults and pediatric patients 10 years): Approved 2014 Heart failure with reduced ejection fraction (HFrEF, adults): Approved 2021 Chronic kidney disease (adults): Approved 2023 Notably, Jardiance is the only SGLT2 inhibitor approved for pediatric diabetes (children 10 years and older), while Farxiga currently has broader heart failure approvals, including HFpEF

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Within the study group, 4,144 liraglutide users and 612 semaglutide users reported gastrointestinal issues, compared to 654 among Contrave users