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Extended, uninterrupted IGF-1 LR3 use can lead to receptor desensitization and may affect insulin sensitivity over time

While free radicals are generated through several things, including normal metabolic processes, strenuous physical activity also induces oxidative stress, whereby the production of free radicals can exceed the capabilities of the antioxidant system to combat them 2

Hepatol Res 45(3):269278 Errafii K, Khalifa O, Al-Akl NS, Arredouani A (2022) Comparative transcriptome analysis reveals that Exendin-4 improves steatosis in HepG2 cells by modulating signaling pathways related to lipid metabolism

Sidorenkov G, Navis G