This process primarily occurs in the liver, the bodys main organ for detoxification.[ref] The CYP450 enzymes have iron and oxygen in them and, through a redox reaction, can make a drug, toxin, or endogenous substance more polar
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Thats why a night out on the drink can feel like one long trip to the bathroom - with each trip leaving your body more and more dehydrated
Genaro LM, Gomes LE, de Freitas Franceschini AP et al (2021) Anti-TNF therapy and immunogenicity in inflammatory bowel diseases: a translational approach