Some people stay nauseated or constipated on semaglutide no matter how slowly they titrate
How might focusing on BMI as a measure of obesity and health overlook other key factors contributing to cardiometabolic risks, and what alternative metrics could provide a more comprehensive evaluation
For patients with prediabetes or diabetes, HbA1c monitoring should follow American Diabetes Association guidelinestypically every three months until glycemic targets are achieved, then at least twice yearly for stable patients
Established Practice in Diabetes Management: Subcutaneous injections are well-established in diabetes treatment, especially for drugs like GLP-1 receptor agonists

Sources Glucagon-Like Peptide-1 Receptor Agonists, PubMed [accessed 16 October 2024] Ozempic 0.5 mg solution for injection in pre-filled pen SmPC, emc [accessed 16 October 2024] Saxenda 6 mg/mL solution for injection in pre-filled pen SmPC, emc [accessed 16 October 2024] Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes, NEJM [accessed 16 October 2024] Semaglutide induces weight loss in subjects with type 2 diabetes regardless of baseline BMI or gastrointestinal adverse events in the SUSTAIN 1 to 5 trials, PubMed [accessed 16 October 2024] Semaglutide 24 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial, The Lancet [accessed 16 October 2024] Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen SmPC, emc [accessed 16 October 2024] Once-Weekly Semaglutide in Adults with Overweight or Obesity, NEJM [accessed 16 October 2024] Patient Reviews Related Weight Loss Treatments Further Reading on Weight Loss Do Appetite Suppressants Work
