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When it comes to side effects, the most common by far is gastrointestinal stomach issues
FAQ: Glutathione and NAC IV Therapy 1
The 2023 American Association of Clinical Endocrinology (AACE) Comprehensive Type 2 Diabetes Algorithm recommends adding an SGLT2 inhibitor with outcomes data when a patient with atherosclerotic cardiovascular disease, CKD, or heart failure does not achieve glycemic targets on metformin alone, placing canagliflozin among the preferred second-line agents in those patient groups [21]
It has appeared across the STEP, SUSTAIN, and PIONEER clinical trial programs, with published literature covering glycemic control, cardiovascular outcomes, and metabolic signaling
Adults take 1 capsule daily with food
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