Also, recent evidence suggests that GSH plays a crucial role in the control of epigenetic mechanisms 3,4,28,29,30,31 either independently or by redox phenomenon
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Oxidized glutathione stimulates the formation of disulfide bonds between adjacent thiol groups in the protein molecule and changes their properties: GSSG + Pt-(SH)2 Pt(S-S) + 2GSH, and also interacts with SH-groups of proteins and forms "mixed disulfides", which changes the properties of proteins, causing dysfunction of cells
In conclusion, the complex interactions between ionizing radiation, microgravity, and astronaut health during space travel are highlighted in this review
The essential fatty acids include -linolenic acid (ALA), an omega-3 fatty acid, and linoleic acid (LA), an omega-6 fatty acid