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Concentrations used in vitro or in animal models vary, but common experimental dosing involves subcutaneous injections in animal studies or topical application in skin models

Primary hippocampal neuron cultures are used to study Dihexa's proposed effects on dendritic spine density and synaptic protein expression, typically measuring morphological changes via fluorescence microscopy and quantifying synaptic marker expression (such as PSD-95 or synaptophysin) relative to untreated controls

Collagen is the most abundant protein in the body and is the primary structural foundation for skin, tendons, and ligaments