Discussion Significantly increased cortisol concentrations in the serum of the studied men after 8 days of water-only fasting and maximum physical exercise indicate the stimulation of a strong stress reaction, which was activated mainly by the fasting intervention
2e and Supplementary Table 1)
These effects share similarities with those of metformin, the first-line medication for type 2 diabetes recommended by NICE
Nevertheless, the profile of pathogen-inducible GSTs could provide a characteristic signature for a particular plant-pathogen interaction
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