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5,12,13 These efforts have yielded six GLP-1 RAsstarting with the development of exendin-4 (Figure 1B)-based exenatide (Figure 1C), followed by liraglutide (Figure 1D), albiglutide, dulaglutide (Figure 1E), lixisenatide, and semaglutide (Figure 1F)that have been approved by the United States Food and Drug Administration (US FDA) to treat type 2 diabetes
Therefore, successfully launching new muscle-preserving therapies will require extensive market shaping activities to create awareness of unmet need around the risk and implications of muscle loss, to build advocacy for the need to treat, the role of novel pharmacotherapeutic approaches and their clinical, economic and patient-relevant benefits
People living in [a] rural area or [a] community with more social-economic challenges were less likely to be prescribed with this treatment. The class of medications called glucagon-like peptide-1 (GLP-1) agonists are prescribed to treat Type 2 diabetes, a metabolic condition that increases the risk of cardiovascular disease
The clinical effects reported in therapeutic studies include abdominal pain, nausea, vomiting, food intolerance, and others
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