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For the first time, we have medications thatwhile not directly targeting sleep apneacan dramatically improve it through significant weight loss
The brain receives stronger fullness cues during and after meals
Lateral hypothalamic circuits for feeding and reward
The GLP-1RA/SGLT2i combination caused a greater body weight loss versus SGLT2i ( = 1.61 kg
This triple agonism distinguishes retatrutide from existing approved agents such as semaglutide (a GLP-1 receptor agonist) and tirzepatide (a dual GIP/GLP-1 agonist)
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