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Food and Drug Administration (FDA) for the drug to treat MASH
A retrospective chart review of 164 patients with T2D who switched from either liraglutide or dulaglutide to semaglutide found that this switch was associated with reductions in HbA1c and weight at 3, 6 and 12 months after the switch [14]
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Tirzepatide (Zepbound): Showed up to 20.9% average weight reduction at the highest dose in the SURMOUNT-1 trial
Wegovy targets physical appetite but may not fully address emotional hunger
What this points to You want a proper loading phase plus several weeks of maintenance
![Semaglutide vs Tirzepatide: Real Weight Loss Results Compared [2026]](https://instantuc.com/wp-content/uploads/2026/01/image.png)
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