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Nutrition and Exercise Still Matter Any GLP-1 medication works better when combined with adequate protein intake, resistance training, and lifestyle changes
P = 0.0004) compared to placebo, without increasing time spent in hypoglycemia (Supplementary Table 12)
The glucagon receptor activation is the key differentiator
Tirzepatide came off the FDAs official drug shortage list in December 2024, and semaglutide followed in February 2025, eliminating the legal pathway that allowed compounding pharmacies to produce copies of the drugs
Experts suggest that the synergy between the two hormones may amplify the therapeutic effects, significantly reducing blood sugar levels and promoting weight loss
