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Long-term human safety data for both peptides remains limited
Halliwell B, Gutteridge JM
Apply topical products as directed, typically twice daily
Is the AOD-9604 peptide approved by Health Canada
Among the numerous partners that interact with NRF2 regulating its activity, two members of the CNC-bZIP protein family BTB and CNC homolog 1 (BACH1) and BTB and CNC homolog 2 (BACH2) are two negative regulators of NRF2: they compete with NRF2 for the binding to ARE sequences of target genes, thereby preventing the production of antioxidant enzymes and cellular defense against toxicity [232, 233]
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