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Lamb JG and Franklin MR
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Menopause can also be induced by therapies that are toxic to the ovaries, such as radiation therapy and some chemotherapies, or by treatment with anti-estrogenic drugs, such as those used to treat endometriosis or breast cancer
The current methods of subcutaneous injection or continuous infusion are not conducive to long-term management, and the development of a drug administration system with high patient compliance (such as oral or weekly injection) is still a major challenge
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