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[18] [19] Phase 2 trial data published in the New England Journal of Medicine (2023) demonstrated substantial weight loss with retatrutide, but also confirmed that gastrointestinal side effects including diarrhoea were among the most commonly reported adverse events

It is derived from a partial sequence of a protein found in human gastric juice and has a molecular weight of approximately 1419.5 Da [1]

Klemettila, J.-P

157 In the mitochondrial pathway, disruption of the outer mitochondrial membrane integrity can lead to mitochondrial outer membrane permeabilization (MOMP)

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