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The hops extract provides rapid, meal-related GLP-1 stimulation through bitter receptor activation
[260] [261] [263] The field that studies these interactions is known as pharmacomicrobiomics
They were originally FDA-approved for Type 2 diabetes and insulin resistance but have since been approved for so many other things, including obesity, sleep apnea, etc., with additional benefits like reduced risk of heart disease
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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