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These contaminants stimulate host cells, including gingival macrophages and fibroblasts, leading to inflammation in periodontal tissue and alveolar bone resorption (Xu et al., 2020

An 18month trial of exenatide showed no significant changes in amyloid or tau in cerebrospinal fluid the clear liquid that surrounds and protects the brain but did reduce amyloidbeta in extracellular vesicles, a potential early biomarker

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