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In the STEP trials, semaglutide 2.4 mg caused vomiting in 24.5% of participants versus 6.3% on placebo
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Our formulation includes B12, which helps reduce the severity of nausea during dose increases
It has also been reported that prostaglandin E2 (PGE2) secretion and cyclooxygenase-2 (COX-2) expression were significantly increased in colon cells exposed to toxin A either in vivo or in vitro (Kim et al., 2007)
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