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They also note several limitations to the work, including the fact that it was done in mouse models, not humans, and that the mice were all male

Diabetes 3 , 16 (2012)

Talk to your prescribing clinician before changing your medication, calories, macros, supplements, exercise, or meal timing, especially if you have diabetes, kidney disease, gallbladder issues, a history of pancreatitis, a history of disordered eating, pregnancy, or any medical condition

Renal effects are primarily related to volume depletion from gastrointestinal side effects rather than direct nephrotoxicity

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