Glutathione production by our bodies naturally decreases with age, but can also be impacted by diet, physical activity, alcohol intake, infections, stress, certain medications, and chronic illness
Only in scenarios which assumed that interventional medications were continued until death did estimated ICERs approach the upper end of what has been commonly considered cost-effectiveness threshold of 357,000 DKK (around 50,000) per QALY [53,54,55]
Going beyond that window introduces increasing risk of potency loss and potential contamination
By modulating the brains dopamine reward system, GLP-1 agonists show promise in reducing cravings and compulsive behaviors associated with various substance use disorders, including alcohol, nicotine, and potentially opioids and stimulants [14, 16, 17]
James Hill: And we know nothing about preferences and cravings and all that