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1 Introduction Diabetic cognitive impairment (DCI), a debilitating neurological complication of diabetes mellitus (DM), is characterized by progressive cognitive decline, chronic neuroinflammation, and irreversible brain structural remodeling ( Two interconnected pathological axes are increasingly implicated in DCI: central sphingolipid metabolism and the gut-brain axis
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Moreover, GSH is related with the transport of endogenous/exogenous molecules to extracellular medium by ABCC1/MRP1 activity
Semaglutide acts on GLP-1 receptors to reduce appetite, while ashwagandha modulates cortisol and stress responses
Kim 2014
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