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They also compared the catalytic rate of GSH reduction induced by single-atom Pd nanozyme, Cu 2-x Te nanozyme, and copper hexacyanoferrate nanozyme (SSNEs) (Figure 1D), ( FIGURE 1 The transition of metal ions valence would also be a powerful strategy for GSH exhaustion

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GSH is oxidized during peroxide disposal by glutathione peroxidase to GSSG (two molecules of GSH bound by disulfide-bond)

Lung cancer cells become much more susceptible to ferroptosis under Nrf2 silencing