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If HSPA1 induction is impaired, cells may have a reduced ability to tolerate heat-induced proteotoxic stress, which can contribute to severe damage during spermatogenesis (Williams et al., 2019
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N Engl J Med 2008 Jun 12
Generally, individual injection doses are smaller than a full IV dose, because very high amounts of NAD under the skin can be uncomfortable
Pills are also easier to transport and produce, says Rozalina McCoy, an endocrinologist and internist at the University of Maryland, adding that she hopes the new FDA approval will increase access to the drugs
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