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Hyperglycemic conditions and the resultant metabolic disorder primarily disrupt autophagy by blocking autophagic flux and compromising lysosomal function, ultimately leading to stagnation of the autophagy pathway (146, 147)

Cirrhosis represents a critical intermediate stage in the progression to hepatocellular carcinoma, which is the most severe outcome for patients with cirrhosis (36)

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There is some concern about inhibition of certain enzymes involved in drug metabolism, potential DNA degradation, iron chelation, and the relationship between curcumin intake (172)

Glutathione IV therapy : IV glutathione treatment should be administered by a licensed professional