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GLP-1 medications are associated with a modest increase in gallbladder events, likely due to rapid weight loss rather than direct effects on the gallbladder
Notably, a meta-analysis of multiple cardiovascular outcome trials (CVOTs) reported no significant difference in AF risk between GLP-1RAs and placebo in participants with type 2 diabetes (OR 0.93
The legality concern applies to the seller, not the buyerif the manufacturer markets the product with prohibited disease claims or the formulation is adulterated, the FDA targets the company, not individual consumers
This method was deemed appropriate given the nature of the dataset and the retrospective design of the study
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