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TB-500 is a synthetic analog of Thymosin Beta 4

Hiccups: Beyond a Simple Reflex: The discussion of hiccups, especially intractable cases and those occurring in sleep, reveals the complexity of this reflex and its potential to signal underlying health issues

doi: 10.1038/s41419-024-07312-2 69 PengW

Beta-arrestin recruitment and receptor internalization vary between agonists at this receptor, and the relationship between internalization rate and sustained signaling is still argued

These findings support the superiority of OW agents in this context and justify their consideration as first-line pharmacologic options when weight recurrence occurs