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5 Briefly, the conversion of dietary precursors into TMA involves four enzymatic pathways, including the choline-utilizing TMA lyase system (CutC/D), the carnitine Rieske-type oxygenase/reductase system (CntA/B), betaine reductase, and TMAO reductase
L-Carnitine+Probio+CLA
On the other hand, exposure to hypobaric hypoxia decreased the ATP and NADPH level in hippocampus which could be a result of impaired mitochondrial functioning on account of reduced availability of oxygen and malfunctioning of the pentose phosphate pathway that generate NADPH and/or overutilization of NADPH under hypoxic condition [26]
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