Umbareen Mahmood, MD, a board-certified plastic surgeon in New York City, says shes now even encountering men and women with already-low BMIs who are using the drugs to lose a few pounds for a big event or beach vacation. Surprisingly, many of these patients are still seeing negative aesthetic side effects, likely due to how rapid the weight loss wasthose who lose weight gradually tend to have better tissue elasticity and skin retractionand also because their margin for loss is smaller given that they were already at a healthy weight for their body. (When someones BMI is low to start, she explains, losing a few pounds can have a significant impact on the little bit of fat you have.) Jerry Chidester, MD, a board-certified plastic surgeon in Draper, Utah, tells me that close to half of his patients are currently using a GLP-1 or have in the past
Patients are randomized in parallel fashion to subcutaneous tirzepatide once weekly or matching placebo
This week the pharmacy compounding, weight loss and anti-aging communities have been abuzz from the October 2, 2024 announcement from the FDA and Eli Lilly that they are removing both of the brand name tirzepatide blockbuster drugs, Mounjaro and Zepbound from the FDA drug shortage list
It works by mimicking growth hormone-releasing hormone (GHRH), essentially extending the bodys natural growth hormone pulses rather than forcing a sudden spike
Alcohol impairs your liver's ability to maintain stable glucose levels, particularly when you're fasting or consuming more than one drink