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Additionally, electrophysiological experiments have shown the direct effects of B vitamins on pain transmission pathways in the spinal cord and thalamus, which explains the observed reduction or loss of pain sensation in clinical patients
The consensus now is that a broad-spectrum antioxidant approach via diet (whole foods) is preferable
(Glutathione) 3 (Cysteine), (Glutamic acid) (Glycine)
This might explain the common x axis intercept in LineweaverBurk plots 11,17,18 , which resemble a non-competitive inhibition pattern with identical dissociation constants for the inhibitor and substrate 52
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