comparative effectiveness of semaglutide and tirzepatide vs bariatric surgery What happens when patients stop taking GLP-1 drugs? New study reveals real world insights Pharmacologic Disruption: How Emerging Weight

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Pharma is innovating to hit even more targets The latest article I saw about the work being done in this class is a study in mice looking at a quintuple agonist (5 different targets!) I almost never write about mice studies because of how preliminary they are and how unlikely a finding in mice is to ever translate into anything useful in humans, but because of the success weve already seen of this drug class as well as the way that hitting more pathways seems to increase efficacy, I thought this was research worth highlighting

Obesity Reviews, 24 (5), 665-674

Juanola-Falgarona 2014