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Options include once-weekly dulaglutide or once-daily liraglutide, though these medications also carry gastrointestinal side effect risks

Per the approved FDA labeling information, individuals must be diagnosed with type 2 diabetes mellitus or be considered obese, with a body mass index (BMI) above certain thresholds

Translating laboratory-discovered resistance-reversal strategies into clinical practice faces multiple barriers, including biological complexity, economic constraints, data integration challenges, ethical concerns, and unequal access to advanced diagnostics and personalized therapies

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Semaglutide mimics the action of the glucagon-like peptide-1 (GLP-1) hormone, which helps regulate blood sugar levels by enhancing insulin secretion, reducing glucagon release, and slowing gastric emptying