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Once participants arrived, they were given a snack (Clif-Bar, Indianapolis, USA) to standardize caloric intake and ensure a similar gastric content prior to alcohol administration
For those with type 2 diabetes, this can delay gastric emptying (which typically leads to an increased feeling of fullness and reduces food intake) and decrease glucagon production (leading to reduced glucose production) when blood sugar levels are elevated
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It is under investigation in preclinical and clinical studies on overweight, obesity, and metabolic disorders, where researchers have examined its effects on body weight and energy intake, including when combined with GLP 1 receptor agonists such as semaglutide, but it is not an approved therapy
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