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However, abrupt discontinuation of GLP-1R agonists in patients with metabolic disorders may lead to rapid weight regain and potential exacerbation of IIH symptoms, as reported in a case study [101]

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A record keeps you accountable to those numbers

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Indeed, patients who were originally described as suffering from deficiencies in the LCAD enzyme were, in fact, found to be harboring pathogenic variants in the ACADVL gene which encodes the VLCAD enzyme