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The delayed gastric emptying does not appear to cause clinically significant impairment of overall digestive enzyme secretion, but it does alter the timing and pattern of digestion

The result does not identify the source or diagnose cardiovascular disease

It is important to note that orlistat can reduce levothyroxine absorption, and the BNF recommends separating administration by at least 4 hours and monitoring thyroid function

In Phase 2, participants were randomized to multiple doses, such as: 1 mg fixed dose 4 mg, starting at 2 mg or 4 mg 8 mg, starting at 2 mg or 4 mg 12 mg, starting at 2 mg All doses were administered subcutaneously once weekly, and dose escalation was intended to improve tolerability

Genentech USA, Inc