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In the STEP 4 trial, participants who had already tolerated a 20-week run-in found continued treatment at the maintenance dose well tolerated
Gray says
RD Lawrence Lecture 2008: Targeting GLP-1 release as a potential strategy for the therapy of Type 2 diabetes
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Probably the improvement in glucose homeostasis contributed to a higher survival rate in animals treated with the QV formulation than untreated diabetic rats and diabetic rats treated with a daily dose of insulin, suggesting that the treatment with formulation may be associated with a low risk of the hypoglycemia that sometimes results from insulin administration 15
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