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More explanatory evidence in the future will require the simultaneous reporting of metabolites/metabolic ratios and cellular phenotypic outputs within a unified network framework, together with the integration of multi-model data stratified by tissue and disease stage, so as to move from pathway-level associations toward definable metabolic nodes and translatable therapeutic windows
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The GLP-1 receptor agonist liraglutide improves memory function and increases hippocampal CA1 neuronal numbers in a senescence-accelerated mouse model of alzheimers disease
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