retatrutide phase 3 triumph Delivers Bariatric-Level Weight Loss in Pivotal TRIUMPH-1 Trial Lilly's retatrutide hits Phase 3

Emerging data suggest that GLP-1 drugs have an anti-inflammatory effect to treat a wide variety of diseases, and the next frontier could be Alzheimers disease now that GLP-1 drugs targeting the condition recently entered phase three trials

Gallstones Gallstones(cholelithiasis) are caused by changes in bile composition and biliary motility

Safety & Side Effects While generally well-tolerated, common side effects include "mild nausea, digestive discomfort, and appetite suppression." These effects typically "subside over time as you acclimate to the medication." 3

Genetic variants in the GLP-1 receptor, differences in gut microbiome composition, and carnitine metabolism may all play a role

Inhibition of GGT (105) and elevated expression of ChaC1/ChaC2 (69,79) are associated with autophagy phenotype