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Similar content being viewed by others This article describes research in our and other laboratories on mitochondrial metabolism of acetyl-L-carnitine (LAC) that has led to the discovery of novel epigenetic mechanisms for the rapid regulation of brain plasticity in multiple rodent models and then has prompted us to uncover a role for this proposed mitochondrial signaling pathway of epigenetic function as a therapeutic target for clinical phenotypes of depression linked to childhood trauma, and implications for Alzheimers disease (Fig

New nausea, vomiting, headache, vision changes, abdominal pain, swelling, high blood pressure, bleeding, leaking fluid, or reduced fetal movement can indicate an obstetric emergency and should not be treated as routine dehydration

2014 Feb;13(1):8-12