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FNDC3B protects steatosis and ferroptosis via the AMPK pathway in alcoholic fatty liver disease
Trends Biochem Sci 41(7):568577 Deguise MO, Pileggi C, De Repentigny Y, Beauvais A, Tierney A, Chehade L, Michaud J, Llavero-Hurtado M, Lamont D, Atrih A, Wishart TM (2021) SMN depleted mice offer a robust and rapid onset model of nonalcoholic fatty liver disease
As a consequence, the main mitochondrial proteome (~1500 proteins) is encoded by the nucleus, translated in the cytosol and imported into the mitochondria through specific translocator complexes (TIM and TOM) of the inner mitochondrial membrane (IMM) and outer mitochondrial membrane (OMM), respectively
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