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The neuroprotective effect of GLP-1RAs through GABAergic modulation not only supports its clinical potential in neurodegenerative diseases such as AD, HD, and Parkinsons diseases (PD), but also adds to our fundamental understanding of GLP-1s pleiotropic molecular network with a special focus on its ocular therapeutic potential
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11 12 GLP-1s lower blood sugar, blood pressure, body weight, and inflammationall of which reduce strain on the heart and blood vessels 13 GLP-1 receptors are found in the heart and arteries, where they may also improve endothelial function, increase nitric oxide, and reduce oxidative stress, helping stabilize plaque and improve how the heart uses energy, especially during stress
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