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This depletion can lead to anemia, and also an increased risk that their breastfed infants become vitamin deficient
In the original NNMT inhibitor research literature, 5-Amino-1MQ was evaluated in cultured adipocytes and diet-induced mouse models to study NNMT-related metabolic biology, including adiposity-related and lipid-related endpoints under defined experimental conditions
When NNMT is overactive, it consumes excess NAD+, leaving less available for these critical processes
PMC 4145307
Pale or Jaundiced Skin: Individuals with B12 deficiency often look pale due to decreased red blood cell production
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