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In phase 2 trials, cagrilintide alone produced dose-dependent reductions in body weight, with participants on the highest dose (4.5 mg weekly) losing roughly 10-15% of body weight over 26 weeks

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Less Common but Serious Concerns Gallbladder disease Pancreatitis (rare) Dehydration from persistent nausea At Florida Endocrinology and Diabetes Center, careful titration and monitoring minimize these risks

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Annually thereafter: Continue monitoring vitamin D, B12, iron, and calcium markers

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