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mechanism matters
In fact, the profound ROS accumulation characteristic of sickle RBCs has been demonstrated to be mainly caused by NADPH oxidase, which is regulated by Rac GTPase [179]
doi:10.1177/0748730418796443
BPC-157 (Body Protection Compound-157) is a 15-amino-acid gastric pentadecapeptide that promotes angiogenesis through VEGF upregulation and protects tissue through nitric oxide system modulation
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