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Others are technically long-term but come with monitoring requirements, side effects, stopping rules or limits on how much weight patients could expect to lose

Phase 2

Research on digital self-monitoring points in the same direction: across 39 trials in a systematic review of digital weight-loss interventions, self-monitoring was associated with superior weight loss

(2025) utilized the TriNetX database and found that semaglutide and the dual GLP-1/GIP agonist tirzepatide were associated with significantly lower risks of all-cause dementia, vascular dementia, and stroke

Frequency and duration may vary depending on the goal and individual needs