doi: 10.1084/jem.20141656 147 ZhangLGuoKZhouJZhangXYinSPengJet al
Over time, that steady output can wear on nearly every system, from the heart and gut to sleep and mood, as the American Psychological Association outlines in its review of how stress affects the body
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Consistently, our T-maze test also exhibited significant improvement in the performance of 5XFAD, as shown by increase in the number of positive turns (Figure 6F) and reduction of errors (Figure 6G), whereas 5XFAD Ppar-null mice and 5XFAD Ppar-Hippo mice did not display any improvement in T maze analyses (Figure 6, F and G), following Hex treatment, indicating a pivotal role of hippocampal PPAR in Hex-mediated improvement in spatial and contextual in 5XFAD mice