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In mice, the loss of JNK1 and JNK2 led to more severe age-related OA and ageing of cartilage and synovium (Loeser et al., 2020), an indication that JNK is a detrimental regulator of joint degeneration
In sum: Uncertain risks plus an unclear benefit equals a trade-off thats just not worth it
and M.A
[3] One study focused on the potential role of the tripeptide concerning dermal papilla cells (DPCs)
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