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2020;5(6): e133429
Its cost-effective because it is a compounded medication, but not because of the quality and effectiveness of its branded counterpart
Lippincott Illustrated Reviews: Biochemistry , 7th ed
702 Mutations in IDH impair its ability to catalyze the conversion of isocitrate to -KG and instead confer neomorphic activity, whereby it reduces -KG to D-2-hydroxyglutarate (D-2HG) in an NADPH-dependent manner
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