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J Am Chem Soc 134(8):39123916 Shang S, Tan Z, Dong S, Danishefsky SJ (2011) An advance in proline ligation
F1000Research (2016) 5
Subsequently, ribosomal protein S6 (RPS6), the subunit of eukaryotic translation initiation factor 2 (eIF2), and eukaryotic translation elongation factor 2 (eEF2) undergo phosphorylation (Dong et al., 2018)
Effects can begin within hours of the first dose, with research showing sleep pressure reported within about 2 hours
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