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Animal studies have shown that compared to wild-type mice, G93A mice exhibit distinct differences in fecal microbiota composition, with increased numbers of Paneth cells, which sense microorganisms and secrete antimicrobial peptides
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene
[published correction appears in BMJ
Int J Cell Biol 2013:180906
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