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Increased Ucp2 favored proton leakage across the inner mitochondrial membrane, depolarizing mitochondria and uncoupling OXPHOS from ATP synthesis, reducing the mitochondrial membrane potential
[36] [37] Los efectos adversos tambin difieren: los inhibidores de SGLT2 aumentan el riesgo de infecciones genitourinarias y cetoacidosis diabtica, mientras que la semaglutida causa principalmente sntomas gastrointestinales
This is not a caution or relative contraindication
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